What happens to the mitochondrial membrane potential in HD patients?

Role of Calcium and Membrane Potential in Neural Function
Neuroscience: Role of Calcium and Membrane Potential in Neural Function

. What happens to the mitochondrial membrane potential in HD patients? Why might that lead to a change in the membrane’s ability to release calcium into the cytoplasm?

. What kinds of effects might the altered intracellular calcium level have on the cell itself?

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. What is excitotoxicity, and how is it related to calcium levels? What role might this play in neurodegeneration?

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